Regenerative Medicine and Amniotic Membrane Application for Vocal Fold Scars and Sulcus

Vocal fold scars and sulcus cause severe vocal problems, but no optimal treatment has been established. In cases, in which the entire lamina propria is occupied by fibrosis vibratory function completely lost, more powerful regeneration materials should be used, or mucosa totally replaced. Amniotic membrane a scaffold material that rich stem cells growth factors high regenerative effect. It can clinically applied many fields. Several studies have already investigated effects of amniotic on animal studies. These shown effective for regeneration. particular, our study showed transplantation an to rabbit induced hyaluronic acid retention suppression collagen deposition after three months without rejection. We hope use will broadly future.